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|Title:||Electrical conductivity measurement in Thiel-embalmed tissue model : relevance to radiofrequency ablation|
|Keywords:||QD Chemistry;R Medicine;QD;R|
|Description:||PA gratefully acknowledges SUPA for funding his Advanced Research Fellowship.;Thiel-embalmed human cadaveric specimens are used widely for biomedical scientific investigation. This Letter reports electrical impedance measurements of Thiel-embalming solutions from 1 Hz to 32 MHz. Compared with other solutions studied, Thiel solution has the lowest impedance throughout the test spectrum. The electrical conductivity of a Thiel-embalmed liver sample exhibited a relatively flat frequency response from 100 to 500 kHz, which is the frequency range used for electro-surgery and radiofrequency tumour ablation (RFA). It measured 5 Sm-1 compared with 0.22 Sm-1 obtained from ex-vivo fresh pig liver. Using finite element modelling and experimental evaluation, the ablation zone obtained from the Thiel-embalmed liver sample was extremely small due to its much higher conductivity. Hence, it is concluded that Thiel-embalmed tissue cannot be used as a reliable model for RFA evaluation.;Postprint;Peer reviewed|
|Other Identifiers:||Wang , Z , Luo , H , Nick , M , Gueorguieva , M , Andre , P , Baker , R T , McLean , D , Brown , S & Cuschieri , A 2014 , ' Electrical conductivity measurement in Thiel-embalmed tissue model : relevance to radiofrequency ablation ' Electronics Letters , vol 50 , no. 16 , pp. 1125-1127 . DOI: 10.1049/el.2014.1934|
PURE UUID: e6956052-d0eb-47e1-85fb-e5e6e327c750
|Type Of Material:||OTHER|
|Appears in Collections:||Chemistry (School of)|
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